(0) Item / $0
Call Us 800.677.9299 | What's up Guest, Login! |

Lipocaine® 5 - Alcohol-free liposomal 5% lidocaine cream all natural

New Product! LIPOCAINE® 5 - Topical Anesthetic Cream with liposomal lidocaine 5%

Shop Lipocaine® maximum concentration lidocaine delivered from liposomes for fast and deep skin numbing;

LIPOCAINE® is a topical anesthetic cream containing lidocaine 5% formulated in liposomes for fast and deep skin numbing. The cream vehicle is composed with 100% naturally derived ingredients with a natural preservative system. Pharmacist formulated; ALCOHOL free. No sting upon application!

LIPOCAINE 5 Highlights

  • FAST AND DEEP PENETRATION - Lidocaine is formulated in liposomes to penetrate the skin without the need of alcohol or other harsh chemicals. This means you get maximum penetration quickly, and maximum numbness. Starts numbing in 3-5 minutes and effective numbing for many procedures at 30 minutes. Best results at 45-60 minutes, even up to 90 minutes for tattoos.
  • MAXIMUM STRENGTH - It contains Lidocaine 5%, the maximum strength available without a prescription. This means relief without a expensive visit to the doctor.
  • LONG LASTING - Numbness lasts approximately double the application time. 60 minutes application gives you 2 hours of numbness.
  • CONVENIENT SIZES - Available in a 4 Oz (113 gram) tube and in a 1 Oz (30 gram) tube. Both with CHILD-RESISTANT caps.
  • ALL NATURAL, VEGAN - All natural cream, FREE of propylene glycol, PEGs, parabens, silicones, petroleum derivatives, artificial colors or fragrances. Natural preservative system. Compare LIPOCAINE®'s ingredients with our competitor’s!
  • ALCOHOL FREE - No sting upon application.

LIPOCAINE® topical anesthetic gel numbs the skin to make every procedure much more comfortable. Why suffer?

Delivers lidocaine quickly and deeply without the use of harsh chemicals or alcohol. No sting upon application! Great to use on the face and sensitive areas. Hypoallergenic and suitable for even the most sensitive skins.

Lipocaine eases the pain of procedures - Alcohol Free, all-natural vehicle

How it works

LIPOCAINE is formulated with 5% lidocaine, the maximum concentration allowed by FDA to be sold without a prescription. Lidocaine is a topical anesthetic molecule that works by temporarily blocking the pathway of pain signals along nerves. It does this by stopping the sodium from entering the nerve ending at the site of the pain. For this to happen, the molecule has to reach the nerve receptors located deep in the skin. By encapsulating lidocaine in liposomes, this process is facilitated. Liposomes are small lipid vesicles that merge with cell membranes and deliver their payload within.

Shop LIPOCAINE® Topical Anesthetic Cream

How to use

Apply LIPOCAINE® topical anesthetic cream in a thin layer to the area of interest. Will start numbing within 2-3 minutes and reach numbness sufficient to make most procedures comfortable in 20-30 minutes. The degree of numbness is variable depending on the individual and the area of the body. As a rule of thumb, the longer the application time, the more effective the anesthetic effect. For some individuals and applications, it works best to apply for 45-60 minutes or even 90 minutes. Do not get discouraged, experiment and find the application time that works best for you. Reapply as needed.
Shop Lipocaine products now

How available

LIPOCAINE® is available in 1 Oz (30 g) and 4 Oz (113 g) tubes with child-resistant caps.

Shop Lipocaine products now

Frequently Asked Questions

Q: What are liposomes?Lidocaine in liposomes
A: Liposomes are lipid vesicles formed by double layers of special phospholipids. They are similar to the natural cell membranes and have the ability to penetrate the stratum corneum of the skin. The vesicles have an interior aqueous compartment and a peripheral lipid compartment within the membrane. Lidocaine is soluble in both compartments and liposomes with a high payload can be prepared. When the liposomes interact with a cell membrane, they deliver the payload into the cell. This delivery mechanism is very helpful in helping medicines cross the skin barrier.

Q: Where is LIPOCAINE® made?
A: It is MADE IN USA as are all of ESBA Lab's products. All of ESBA Laboratories products are Pharmacist developed and manufactured in the United States.

Q: How does LIPOCAINE® smell?
A: It is virtually odorless. Does not contain solvents like alcohol or propyleneglycol, or any kind of fragrance.

Q: How is LIPOCAINE® preserved?
A: It is preserved with Caprylhydroxamic Acid; an amino acid derived from coconut oil. Not only is it plant-based and non-toxic, when combined with other natural glycols in our formulation, it provides guaranteed, broad-spectrum performance against bacteria and fungi. Plus, it’s Whole Foods Premium Body Care approved, and their standards, developed by a team of scientists over the course of years, are some of the strictest available. In the world of preservatives, this little amino acid is a real winner!


Lidocaine 5 % in a non-oily cream with Allantoin, Aloe Barbadensis Leaf Extract, Beta-Sitosterol, Caprylhydroxamic Acid, Cetyl Alcohol, Cetyl Palmitate, Vegetable Glycerin, Glyceryl Caprylate, Isostearyl Alcohol, Lecithin (Sunflower, non GMO), Purified Water, Sucrose Distearate, Sucrose Stearate , Tocopheryl Acetate, Triethylcitrate, Xanthan Gum.

Does NOT contain: parabens, PEGs, propyleneglycol, petrolatum, mineral oil, artificial color or fragrances, GMO derived ingredients, alcohol, artificial preservatives, color or fragrances.

Shop Lipocaine products now

THE INFORMATION IN THIS WEBSITE IS FOR INFORMATION ONLY AND IS NOT INTENDED TO BE CONSTRUED AS MEDICAL ADVICE. Please consult your doctor about your condition and follow his/her recommendations.