CLINICAL REPORTS

"Newer Anesthetics Block Nd-Yag Pain"

Cosmetic Surgery Times, in its April 2001 issue, published an interview with Dr Joshua Fogelman, principal investigator of a double-blind, placebo-controlled clinical trial in 24 patients comparing the efficacy of TOPICAINE® 4%, Ela-Max 5% and EMLA. TOPICAINE® 4% showed the best efficacy overall.
NOTE: In this study, the product was tested under occlusion. ESBA LABORATORIES DOES NOT RECOMMEND OCCLUSION. Read the article (Acrobat .pdf file. Opens in a new window).

"30 Minute Topical Application Blocks Nd-Yag Pain"

Cosmetic Surgery Times, in its July 2000 issue, published an interview with Dr Paul M. Friedman, one of the investigators in a double-blind, placebo-controlled clinical trial in 24 patients comparing the efficacy of TOPICAINE® 4%, Ela-Max 5% and EMLA. TOPICAINE® 4% showed the best efficacy overall.
NOTE: In this study, the product was tested under occlusion. ESBA LABORATORIES DOES NOT RECOMMEND OCCLUSION. Read the article (Acrobat .pdf file. Opens in a new window).

"Topical Anesthetics: EMLA and Beyond"

Review article on seven anesthetics by Dr Paul Friedman; Dr Erick Mafong, Edward Friedman BS and Dr Roy Geronimus, published in Dermatologic Surgery, December 2001.
NOTE: In this study, the product was tested under occlussion. ESBA LABORATORIES DOES NOT RECOMMEND OCCLUSION. Read the article (Acrobat .pdf file. Opens in a new window).

"Chemical Peels Cure Darker Skin"

Article published in Dermatology Times, August 2002, describing the work of Dr Harold Pierce, an innovative Philadelphia dermatologist that uses TOPICAINE® 4% prior to chemical peels and wound debridement.
NOTE: Chemical peels and wound debridement are off-label uses of the product. Only physicians can use medicinal products for off-label uses. Read the article. (Acrobat .pdf file. Opens in a new window).

"Topical Triple-Anesthetic Gel Compared With 3 Topical Anesthetics"

Dr Min-Wei Christine Lee evaluated the efficacy of 3 leading brands of topical anesthetics (TOPICAINE 4%, Ela-Max 5% and EMLA) and compared it to a compounded triple anesthetic "BLT". The study was done in 30 patients and the anesthetics and placebo control were randomly applied to different sites in the arm of the patients. The study was published in Cosmetic Dermatology, Vol 16 No 4 April 2003 (35-38).
NOTE: In this study, the product was tested under occlusion. ESBA LABORATORIES DOES NOT RECOMMEND OCCLUSION. Read the article (Acrobat .pdf file. Opens in a new window).